Human Transportin 1 (TNPO1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TNPO1
Locus ID	3842
Kit Components	GA102606G1, Transportin 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102606G2, Transportin 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102606G3, Transportin 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002270, NM_153188, NM_001364292, NM_001364295, NM_001364296, NM_001364293, NM_001364294
Synonyms	IPO2; KPNB2; MIP; MIP1; TRN
Summary	This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]

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