Human JAK3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	JAK3
Locus ID	3718
Kit Components	GA102504G1, JAK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102504G2, JAK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102504G3, JAK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000215
Synonyms	JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Summary	The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]

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