Human ITIH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ITIH1
Locus ID	3697
Kit Components	GA102486G1, ITIH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102486G2, ITIH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102486G3, ITIH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166434, NM_001166435, NM_001166436, NM_002215
Synonyms	H1P; IATIH; IGHEP1; ITI-HC1; ITIH; SHAP
Summary	This gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015]

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