Human IDI1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IDI1
Locus ID	3422
Kit Components	GA102315G1, IDI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102315G2, IDI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102315G3, IDI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317955, NM_001317956, NM_001317957, NM_004508, NR_134300, NR_134301
Synonyms	IPP1; IPPI1
Summary	IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008]

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