Human Isoleucyl tRNA synthetase (IARS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IARS1
Locus ID	3376
Kit Components	GA102296G1, Isoleucyl tRNA synthetase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102296G2, Isoleucyl tRNA synthetase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102296G3, Isoleucyl tRNA synthetase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002161, NM_013417, NR_073446
Synonyms	GRIDHH; IARS1; ILERS; ILRS; IRS; PRO0785
Summary	Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]

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