Human 5 HT1F (HTR1F) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HTR1F
Locus ID	3355
Kit Components	GA102283G1, 5 HT1F gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102283G2, 5 HT1F gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102283G3, 5 HT1F gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000866, NM_001322208, NM_001322209, NM_001322210
Synonyms	5-HT-1F; 5-HT1F; 5HT6; HTR1EL; MR77
Summary	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.[UniProtKB/Swiss-Prot Function]

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