Human Hsp40 (DNAJB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNAJB1
Locus ID	3337
Kit Components	GA102272G1, Hsp40 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102272G2, Hsp40 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102272G3, Hsp40 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001300914, NM_001313964, NM_006145
Synonyms	Hdj1; Hsp40; HSPF1; RSPH16B; Sis1
Summary	This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

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