Human ERAS activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERAS
Locus ID	3266
Kit Components	GA102232G1, ERAS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102232G2, ERAS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102232G3, ERAS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NG_001143, NM_181532
Synonyms	HRAS2; HRASP
Summary	This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]

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