Human HPD activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HPD
Locus ID	3242
Kit Components	GA102224G1, HPD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102224G2, HPD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102224G3, HPD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001171993, NM_002150
Synonyms	4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD
Summary	The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

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