Human HOXB5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HOXB5
Locus ID	3215
Kit Components	GA102199G1, HOXB5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102199G2, HOXB5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102199G3, HOXB5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002147
Synonyms	HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
Summary	This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]

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