Human NUR77 (NR4A1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NR4A1
Locus ID	3164
Kit Components	GA102158G1, NUR77 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102158G2, NUR77 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102158G3, NUR77 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001202233, NM_001202234, NM_002135, NM_173157, NM_173158
Synonyms	GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3
Summary	This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

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