Human HIVEP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HIVEP1
Locus ID	3096
Kit Components	GA102111G1, HIVEP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102111G2, HIVEP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102111G3, HIVEP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002114
Synonyms	CIRIP; CRYBP1; GAAP; MBP-1; PRDII-BF1; Schnurri-1; ZAS1; ZNF40; ZNF40A
Summary	This gene encodes a transcription factor belonging to the ZAS family, members of which are large proteins that contain a ZAS domain - a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specifically to the DNA sequence motif, GGGACTTTCC, found in the enhancer elements of several viral promoters, including human immunodeficiency virus (HIV), and to related sequences found in the enhancer elements of a number of cellular promoters. This protein binds to this sequence motif, suggesting a role in the transcriptional regulation of both viral and cellular genes. [provided by RefSeq, Oct 2011]

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