Human Hemoglobin subunit delta (HBD) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HBD
Locus ID	3045
Kit Components	GA102073G1, Hemoglobin subunit delta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102073G2, Hemoglobin subunit delta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102073G3, Hemoglobin subunit delta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000519
Synonyms	delta-globin chain; delta globin; hemoglobin, delta; OTTHUMP00000069639
Summary	The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]

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