Human HADHSC (HADH) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HADH
Locus ID	3033
Kit Components	GA102063G1, HADHSC gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102063G2, HADHSC gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102063G3, HADHSC gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001184705, NM_005327, NM_001331027
Synonyms	HAD; HADH1; HADHSC; HCDH; HHF4; MSCHAD; SCHAD
Summary	This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]

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