Human Glycophorin C (GYPC) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GYPC
Locus ID	2995
Kit Components	GA102033G1, Glycophorin C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102033G2, Glycophorin C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102033G3, Glycophorin C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256584, NM_002101, NM_016815
Synonyms	CD236; CD236R; GE; GPC; GPD; GYPD; PAS-2
Summary	Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

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