Human Uroguanylin (GUCA2B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GUCA2B
Locus ID	2981
Kit Components	GA102022G1, Uroguanylin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102022G2, Uroguanylin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102022G3, Uroguanylin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_007102
Synonyms	GCAP-II; UGN
Summary	This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. [provided by RefSeq, Nov 2015]

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