Human Gelsolin (GSN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSN
Locus ID	2934
Kit Components	GA101984G1, Gelsolin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101984G2, Gelsolin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101984G3, Gelsolin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000177, NM_001127662, NM_001127663, NM_001127664, NM_001127665, NM_001127666, NM_001127667, NM_001258029, NM_001258030, NM_198252, NM_001353053, NM_001353054, NM_001353055, NM_001353056, NM_001353057, NM_001353058, NM_001353059, NM_001353060, NM_001353061, NM_001353062, NM_001353063, NM_001353064, NM_001353065, NM_001353066, NM_001353067, NM_001353068, NM_001353069, NM_001353070, NM_001353071, NM_001353072, NM_001353073, NM_001353074, NM_001353075, NM_001353076, NM_001353077, NM_001353078
Synonyms	ADF; AGEL
Summary	The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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