Human Gastrin Releasing Peptide (GRP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRP
Locus ID	2922
Kit Components	GA101977G1, Gastrin Releasing Peptide gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101977G2, Gastrin Releasing Peptide gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101977G3, Gastrin Releasing Peptide gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001012512, NM_001012513, NM_002091
Synonyms	BN; GRP-10; preproGRP; proGRP
Summary	This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

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