Human GATA4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GATA4
Locus ID	2626
Kit Components	GA101747G1, GATA4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101747G2, GATA4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101747G3, GATA4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308093, NM_001308094, NM_002052
Synonyms	ASD2; TACHD; TOF; VSD1
Summary	This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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