Human GALNS activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GALNS
Locus ID	2588
Kit Components	GA101728G1, GALNS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101728G2, GALNS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101728G3, GALNS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000512, NM_001323543, NM_001323544
Synonyms	GalN6S; GALNAC6S; GAS; MPS4A
Summary	This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008]

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