Human GABRR2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GABRR2
Locus ID	2570
Kit Components	GA101713G1, GABRR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101713G2, GABRR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101713G3, GABRR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002043
Synonyms	GABA-C receptor, rho-2 subunit; gamma-aminobutyric acid (GABA) receptor, rho 2; OTTHUMP00000040625
Summary	Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability. [provided by RefSeq, Apr 2016]

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