Human GABA B Receptor 1 (GABBR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GABBR1
Locus ID	2550
Kit Components	GA101694G1, GABA B Receptor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101694G2, GABA B Receptor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101694G3, GABA B Receptor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001319053, NM_001470, NM_021903, NM_021904, NM_021905
Synonyms	GABABR1; GABBR1-3; GB1; GPRC3A
Summary	This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016]

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