Human Frizzled 2 (FZD2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FZD2
Locus ID	2535
Kit Components	GA101684G1, Frizzled 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101684G2, Frizzled 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101684G3, Frizzled 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001466
Synonyms	fz-2; Fz2; fzE2; hFz2
Summary	This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]

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