Human Folate Binding Protein (FOLR1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FOLR1
Locus ID	2348
Kit Components	GA101645G1, Folate Binding Protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101645G2, Folate Binding Protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101645G3, Folate Binding Protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000802, NM_016724, NM_016725, NM_016729, NM_016730, NM_016731
Synonyms	FBP; FOLR
Summary	The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

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