Human FKBP25 (FKBP3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FKBP3
Locus ID	2287
Kit Components	GA101600G1, FKBP25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101600G2, FKBP25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101600G3, FKBP25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002013
Synonyms	FKBP-3; FKBP-25; FKBP25; PPIase
Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]

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