Human Fatty Acid Synthase (FASN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FASN
Locus ID	2194
Kit Components	GA101533G1, Fatty Acid Synthase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101533G2, Fatty Acid Synthase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101533G3, Fatty Acid Synthase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004104
Synonyms	FAS; OA-519; SDR27X1
Summary	The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]

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