Human EYA1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EYA1
Locus ID	2138
Kit Components	GA101490G1, EYA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101490G2, EYA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101490G3, EYA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000503, NM_001288574, NM_001288575, NM_172058, NM_172059, NM_172060, NM_001370334, NM_001370335, NM_001370333, NM_001370336
Synonyms	BOP; BOR; BOS1; OFC1
Summary	This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2013]

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