Human XPF (ERCC4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ERCC4
Locus ID	2072
Kit Components	GA101449G1, XPF gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101449G2, XPF gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101449G3, XPF gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005236
Synonyms	ERCC11; FANCQ; RAD1; XFEPS; XPF
Summary	The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009]

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