Human Aminopeptidase A (ENPEP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ENPEP
Locus ID	2028
Kit Components	GA101409G1, Aminopeptidase A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101409G2, Aminopeptidase A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101409G3, Aminopeptidase A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001977
Synonyms	APA; CD249; gp160
Summary	The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020]

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