Human Non Neuronal Enolase (ENO1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ENO1
Locus ID	2023
Kit Components	GA101406G1, Non Neuronal Enolase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101406G2, Non Neuronal Enolase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101406G3, Non Neuronal Enolase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001201483, NM_001428, NM_001353346
Synonyms	ENO1L1; MPB1; NNE; PPH
Summary	This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]

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