Human EN1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EN1
Locus ID	2019
Kit Components	GA101402G1, EN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101402G2, EN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101402G3, EN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001426
Synonyms	engrailed homeobox 1; engrailed homolog 1; OTTHUMP00000162091
Summary	Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]

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