Human EHHADH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EHHADH
Locus ID	1962
Kit Components	GA101360G1, EHHADH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101360G2, EHHADH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101360G3, EHHADH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001166415, NM_001966
Synonyms	ECHD; FRTS3; L-PBE; LBFP; LBP; PBFE
Summary	The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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