Human EGFR activation kit by CRISPRa

CAT#: GA101355

EGFR CRISPRa kit - CRISPR gene activation of human epidermal growth factor receptor



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
EGFR mouse monoclonal antibody,clone 11H7, Biotinylated
    • 100 ul

CNY 3,990.00


EGFR (Myc-DDK-tagged)-Human epidermal growth factor receptor (EGFR), transcript variant 2
    • 10 ug

CNY 4,680.00
CNY 7,315.00


EGFR L858R mouse monoclonal antibody,clone OTI2F5
    • 30 ul

CNY 800.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol EGFR
Locus ID 1956
Kit Components

GA101355G1, EGFR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101355G2, EGFR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101355G3, EGFR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_005228, NM_201282, NM_201283, NM_201284, NM_001346897, NM_001346898, NM_001346899, NM_001346900, NM_001346941
Synonyms ERBB; ERBB1; HER1; mENA; NISBD2; PIG61
Summary The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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