Human Flamingo homolog 1 (CELSR3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CELSR3
Locus ID	1951
Kit Components	GA101350G1, Flamingo homolog 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101350G2, Flamingo homolog 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101350G3, Flamingo homolog 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001407
Synonyms	ADGRC3; CDHF11; EGFL1; FMI1; HFMI1; MEGF2; RESDA1
Summary	This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]

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