Human Endothelin 2 (EDN2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	EDN2
Locus ID	1907
Kit Components	GA101328G1, Endothelin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101328G2, Endothelin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101328G3, Endothelin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302269, NM_001956, NR_126098
Synonyms	ET-2; ET2; PPET2
Summary	This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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