Human DOCK1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DOCK1
Locus ID	1793
Kit Components	GA101247G1, DOCK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101247G2, DOCK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101247G3, DOCK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290223, NM_001380
Synonyms	ced5; DOCK180
Summary	This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

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