Human DYNC1I1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DYNC1I1
Locus ID	1780
Kit Components	GA101238G1, DYNC1I1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101238G2, DYNC1I1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101238G3, DYNC1I1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001135556, NM_001135557, NM_001278421, NM_001278422, NM_004411
Synonyms	DNCI1; DNCIC1
Summary	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.[UniProtKB/Swiss-Prot Function]

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