Human DNase gamma (DNASE1L3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNASE1L3
Locus ID	1776
Kit Components	GA101235G1, DNase gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101235G2, DNase gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101235G3, DNase gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001256560, NM_004944
Synonyms	DHP2; DNAS1L3; LSD; SLEB16
Summary	This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

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