Human DNA2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNA2
Locus ID	1763
Kit Components	GA101227G1, DNA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101227G2, DNA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101227G3, DNA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080449, NR_102264
Synonyms	DNA2L; hDNA2
Summary	This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

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