Human SARDH activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SARDH
Locus ID	1757
Kit Components	GA101221G1, SARDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101221G2, SARDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101221G3, SARDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001134707, NM_007101
Synonyms	BPR-2; DMGDHL1; SAR; SARD; SDH
Summary	This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]

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