Human DIAPH1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DIAPH1
Locus ID	1729
Kit Components	GA101199G1, DIAPH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101199G2, DIAPH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101199G3, DIAPH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001079812, NM_001314007, NM_005219
Synonyms	DFNA1; DIA1; DRF1; hDIA1; LFHL1
Summary	This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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