Human GSDME activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSDME
Locus ID	1687
Kit Components	GA101189G1, GSDME gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101189G2, GSDME gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101189G3, GSDME gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001127453, NM_001127454, NM_004403
Synonyms	ICERE-1
Summary	Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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