Human DDOST activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DDOST
Locus ID	1650
Kit Components	GA101164G1, DDOST gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101164G2, DDOST gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101164G3, DDOST gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005216
Synonyms	AGER1; CDG1R; OKSWcl45; OST; OST48; WBP1
Summary	This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]

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