Human Drebrin (DBN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DBN1
Locus ID	1627
Kit Components	GA101145G1, Drebrin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101145G2, Drebrin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101145G3, Drebrin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004395, NM_080881, NM_001363541, NM_001364152, NM_001364151
Synonyms	D0S117E
Summary	The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

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