Human DAB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DAB1
Locus ID	1600
Kit Components	GA101124G1, DAB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101124G2, DAB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101124G3, DAB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021080, NM_001353980, NM_001353983, NM_001353985, NM_001353986, NM_001365792, NM_001365793, NM_001365794, NM_001365795
Synonyms	disabled homolog 1; disabled homolog 1 (Drosophila); OTTHUMP00000010045; OTTHUMP00000011753
Summary	The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]

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