Human CYP4B1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CYP4B1
Locus ID	1580
Kit Components	GA101110G1, CYP4B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101110G2, CYP4B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101110G3, CYP4B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000779, NM_001099772, NM_001319161, NM_001319162, NM_001319163, NR_135003
Synonyms	CYPIVB1; P-450HP
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jan 2016]

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