Human delta 2 Catenin (CTNND2) activation kit by CRISPRa
CAT#: GA101062
CTNND2 CRISPRa kit - CRISPR gene activation of human catenin delta 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | CTNND2 |
Locus ID | 1501 |
Kit Components | GA101062G1, delta 2 Catenin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101062G2, delta 2 Catenin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101062G3, delta 2 Catenin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001288715, NM_001288716, NM_001288717, NM_001332, NR_109988, NM_001364128 |
Synonyms | GT24; NPRAP |
Summary | This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN224464 | CTNND2 - human gene knockout kit via CRISPR, HDR mediated |
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KN224464LP | CTNND2 - human gene knockout kit via CRISPR, HDR mediated |
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KN224464RB | CTNND2 - human gene knockout kit via CRISPR, HDR mediated |
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