Human CTNS activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTNS
Locus ID	1497
Kit Components	GA101059G1, CTNS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101059G2, CTNS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101059G3, CTNS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031681, NM_004937
Synonyms	CTNS-LSB; PQLC4
Summary	This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

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