Human Cystathionase (CTH) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTH
Locus ID	1491
Kit Components	GA101055G1, Cystathionase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101055G2, Cystathionase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101055G3, Cystathionase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001190463, NM_001902, NM_153742
Synonyms	MGC9471
Summary	This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

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