Human CRY2 activation kit by CRISPRa

CAT#: GA100990

CRY2 CRISPRa kit - CRISPR gene activation of human cryptochrome circadian regulator 2



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol CRY2
Locus ID 1408
Kit Components

GA100990G1, CRY2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100990G2, CRY2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100990G3, CRY2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001127457, NM_021117
Synonyms HCRY2; PHLL2
Summary This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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